Papain 500 TU | 100% Pure & Raw | Food Supplement 20 capsules

The Herbal Remedies Clinical Series® — Papain 500 TU

100% Pure & Raw | Food Supplement | 20 Capsules

Papain is a powerful proteolytic enzyme derived from the latex of unripe Carica papaya fruit. Standardised to 500 Tyrosine Units (TU) per capsule, this raw, unprocessed formulation delivers enzymatic activity in its most bioavailable form — without fillers, binders, or synthetic additives.

Key Benefits

• Supports Digestion* — Papain catalyses the hydrolysis of peptide bonds in dietary proteins, facilitating more efficient breakdown and absorption of amino acids in the gastrointestinal tract.
• Promotes Protein Breakdown* — As a cysteine protease, papain cleaves a broad spectrum of protein substrates, supporting the body's natural digestive processes both in the stomach and small intestine.
• Reduces Inflammation and Swelling* — Papain exhibits systemic proteolytic activity when absorbed intact across the intestinal mucosa. Clinical observations suggest it may modulate inflammatory mediators, supporting recovery from soft tissue swelling.
• Sore Throat and Pharynx Relief* — Topical and systemic proteolytic action may help reduce localised inflammation in the pharyngeal mucosa, offering symptomatic relief from throat irritation.

Clinical & Research Evidence

Papain's enzymatic and anti-inflammatory properties have been the subject of multiple peer-reviewed investigations:

• Proteolytic activity: Papain is classified as a cysteine endopeptidase (EC 3.4.22.2) and has been extensively characterised in biochemical literature for its broad substrate specificity (Mitchel & Harrington, Biochemistry, 1968).
• Systemic absorption: Studies have demonstrated that orally administered plant-derived proteases, including papain, can be absorbed intact through the intestinal epithelium and exert systemic effects (Seifert et al., Arzneimittelforschung, 1990).
• Anti-inflammatory action: A randomised controlled trial published in Phytomedicine (Bhatt et al., 2004) found that enzyme combinations including papain significantly reduced post-operative oedema and pain compared to placebo.
• Digestive support: Research in Food Chemistry (Nitsawang et al., 2006) confirmed papain's efficacy in hydrolysing meat proteins under simulated gastrointestinal conditions, supporting its use as a digestive aid.

Suggested Use

Take 1 capsule once or twice daily, preferably after meals. Can be taken directly, or with water, tea, or milk.

Contents

20 Capsules | Papain 500 TU per capsule

*These statements have not been evaluated by the MHRA. This product is not intended to diagnose, treat, cure, or prevent any disease. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.